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In the FDA review, African American smokers of menthols were less likely to stop smoking than their regular cigarette smoking counterparts due menthol's ability to increase dependency on nicotine

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Clinical trials analysing a class of cancer medication called small-molecule tyrosine kinase inhibitors, which targets a family of proteins that are mutated in many types of cancer, showed that never-smokers, individuals with adenocarcinoma, women and people with east Asian ancestry were more likely to respond well to the drugs than people with a history of smoking 2

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